SureSelect - Performance

SureSelect is the market leading target enrichment solution and has enabled geneticists worldwide to perform cutting edge research which has led to the greatest number discoveries and peer-reviewed publications when compared to competing products. Researchers have been this successful because of the high performance of the SureSelect technology. Adapted from the hybrid selection method originally developed by Gnirke et al *at the Broad Institute and continually improved since release in 2009, the SureSelect platform of products offers researchers a very reliable, cost-effective and consistent method for querying genomic targets of interest across a variety of species.

See How SureSelect Human All Exon V4 and V4+UTRs Delivers The BEST Performance for the Lowest Overall Cost.


Fig. 1 High Percent on Target and Efficient Coverage

The SureSelect Human All ExonV4 designs show high specificity and yield efficient coverage with only 4Gb to 6Gb of sequencing. The SureSelect designs show considerably better performance compared to 5Gb of sequencing using competitor I's product. New SureSelect design algorithms and highly optimized protocols lead to highly efficient target enrichment.


Fig. 2 High Uniformity of Coverage

A.SureSelect Human All Exon v4 – 51Mb (4Gb seq) B. Select Human All Exon v4+UTRs – 71Mb (6Gb seq)

 

The SureSelect Human All Exon v4 kits have been designed with new algorithms to bring market-leading read depth uniformity to researchers interested in targeting both coding content as well as UTRs. This high degree of uniformity combines with the high specificity of SureSelect to enable researchers to finish human exome studies much faster and with greater confidence than with competing exome platforms.

 

* Nature Biotechnology 27, 182 - 189 (2009)

 
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