Constitutional Disease Research Panels

Developed in collaboration with leading medical genetics experts, these constitutional panels provide deep coverage of targets enabling clinical researchers to confidently identify mutations, indels and CNVs.

Expert-optimized content
  • Highly targeted content enabling analysis of regions implicated in rare disease pathogenesis
Fast track to answers
  • Proven, high-performing capture oligos are coupled with highly efficient SureSelect and HaloPlex workflows, providing faster time to results and compatibility with samples of limited availability (high throughput or benchtop sequencers)
Comprehensive Workflow Solution
  • Accelerated sample to categorized variants with SureCall


ClearSeq Inherited Disease
A highly targeted design that enables comprehensive analysis of only those 2,742 genes known to cause inherited disorders
Compatible with SureSelect,XT and XT2

ClearSeq Cardiomyopathy
Designed specifically for inherited forms of cardiomyopathy including hypertrophic, dilated and right
Compatible with HaloPlexHS and HaloPlex


Made to order via SureDesign:

ClearSeq Arrythmia
Target genomic regions in 20 genes known to be linked to four inherited arrhythmia-related heart disorders
Compatible with HaloPlex

ClearSeq Noonan Syndrome
Target a comprehensive set of kinases and kinase related transcripts for enrichment, including over 500 kinases and 612 genes
Compatible with HaloPlex

ClearSeq Connective Tissue Disorders
Focus on 40 genes known to play an important role in inherited forms of connective tissue disorder including Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome, thoracic aortic aneurysm and dissection (TAAD), Stickler syndrome and Osteogenesis imperfecta
Compatible with HaloPlex

ClearSeq ICCG
Interrogate genetic changes in 180 genes defined by the International Collaboration for Clinical Genomics (ICCG) consortium
Compatible with HaloPlex

ClearSeq X-chromosome
Create a comprehensive X-chromosome mutation profile using a single panel
Compatible with HaloPlex

For Research Use Only. Not for Use in Diagnostic Procedures.

Product Catalog Kit Size Quantity Price  
ClearSeq Inherited Disease,XT

Capture library sufficient for 16 hybridizations

5190-7518 $3,790.00
ClearSeq Inherited Disease,XT

Capture library sufficient for 96 hybridizations

Certificate of Analysis
5190-7519 $20,468.00
ClearSeq Inherited Disease, auto,XT

Capture library sufficient for 96 hybridizations with overage for automation

Certificate of Analysis
5190-7520 $20,468.00
ClearSeq Inherited Disease Plus,XT

Capture library sufficient for 16 hybridizations

Certificate of Analysis
5190-7521 $13,514.00
ClearSeq Inherited Disease Plus, XT

Capture library sufficient for 96 hybridizations

5190-7522 $81,082.00
ClearSeq Inherited Disease Plus, auto, XT

Capture library sufficient for 96 hybridizations with overage for automation

5190-7523 $81,082.00
ClearSeq Inherited Disease,XT2

Capture library sufficient for 16 hybridizations

Certificate of Analysis
5190-7524 $3,032.00
ClearSeq Inherited Disease,XT2

Capture library sufficient for 96 libraries (8 samples pooled per capture)

Certificate of Analysis
5190-7525 $16,414.00
ClearSeq Inherited Disease,auto,XT2

Capture library sufficient for 96 libraries (8 samples pooled per capture) with overage for automation

Certificate of Analysis
5190-7526 $16,414.00
ClearSeq Inherited Disease Plus, XT2

Capture library sufficient for 16 libraries (8 samples pooled per capture)

5190-7527 $12,669.00
ClearSeq Inherited Disease Plus, XT2

Capture library sufficient for 96 libraries (8 samples pooled per capture)

5190-7528 $76,014.00
ClearSeq Inherited Disease Plus, auto, XT2

Capture library sufficient for 96 libraries (8 samples pooled per capture) with overage for automation

5190-7529 $76,014.00
ClearSeq Cardiomyopathy, HS, ILM, 16

ClearSeq Cardiomyopathy panel compatible with HaloPlexHS for Illumina sequencers, 16rxn

Certificate of Analysis
G9943A $2,800.00
ClearSeq Cardiomyopathy, HS, ILM, 96

ClearSeq Cardiomyopathy panel compatible with HaloPlexHS for Illumina sequencers, 96rxn

Certificate of Analysis
G9943B $15,168.00
ClearSeq Cardiomyopathy, ILM

HaloPlex Cardiomyopathy kit contains probes, reagents and HaloPlex Magnetic Beads sufficient for 16 samples. Compatible with Illumina sequencing

G9908A $2,884.00
ClearSeq Cardiomyopathy, ILM

HaloPlex Cardiomyopathy kit contains probes, reagents and HaloPlex Magnetic Beads sufficient for 96 samples. Compatible with Illumina sequencing

G9908B $15,623.00