HaloPlexHS - NEW

The detection of somatic variants in heterogeneous cell populations is crucial in a wide variety of applications such as cancer genetics and immunological diversity. Unlike inherited mutations, somatic variants often occur at low allele frequencies that require sensitive methods for detection. HaloPlexHS is a high sensitivity amplicon-based targeted sequencing method based on the HaloPlex technology that incorporates molecular barcodes in the DNA library, allowing for the identification of duplicate reads hence significantly improving base calling accuracy even at low allelic frequencies compared to conventional NGS methods. Combined with the flexibility of panel customization up to 5Mb and an accelerated workflow of less than 6hr starting with 50ng gDNA, HaloPlexHS is well-suited for accurate rare variant detection in clinical research.

Unparalleled Sensitivity

  • Uniquely tag DNA fragments with more than a million 10-nt molecular barcodes
  • Confidently detect mutations present at below 1% allele frequency in genetically heterogeneous samples

Superior Accuracy

  • Differentiation of true variants from PCR or formalin fixation artifacts by targeting both DNA strands
  • High on-target specificity and deep coverage of target bases so key variants are not missed

Accelerated Solution

  • Complete target enrichment in less than 6hr from only 50ng of gDNA
  • From raw data to categorized mutations in 3 steps using SureCall data analysis software


To start your HaloPlexHS Illumina and ION custom design, use the SureDesign online tool

HaloPlexHS also provides molecular-barcoded target enrichment for catalog ClearSeq AML and ClearSeq Cancer Research panels. Learn more >

For Research Use Only. Not for Use in Diagnostic Procedures.

Product Catalog Kit Size Quantity Price  
HaloPlexHS 1-500kb, ILMFST, 48

HaloPlex Target Enrichment for 1-500kb target region incorporating molecular barcodes and compatible with Illumina sequencers, 48rxn

G9931C $12,000.00
HaloPlexHS 1-500kb, ILMFST, 96

HaloPlex Target Enrichment for 1-500kb target region incorporating molecular barcodes and compatible with Illumina sequencers, 96rxn

G9931B  
HaloPlexHS 501kb - 2.5Mb, ILM, 48

HaloPlex Target Enrichment for 501kb-2.5Mb target region incorporating molecular barcodes and compatible with Illumina sequencers, 48rxn

G9941C $16,800.00
HaloPlexHS 501kb - 2.5Mb, ILM, 96

HaloPlex Target Enrichment for 501kb-2.5Mb target region incorporating molecular barcodes and compatible with Illumina sequencers, 96rxn

G9941B  
HaloPlexHS 2.6Mb - 5Mb, ILM, 48

HaloPlex Target Enrichment for 2.6 - 5Mb target region incorporating molecular barcodes and compatible with Illumina sequencers, 48rxn

G9951C $21,600.00
HaloPlexHS 2.6Mb - 5Mb, ILM, 96

HaloPlex Target Enrichment for 2.6 - 5Mb target region incorporating molecular barcodes and compatible with Illumina sequencers, 96rxn

G9951B  
HaloPlexHS 1-250kb, ION, 48

HaloPlex Target Enrichment for 1-250kb target region incorporating molecular barcodes and compatible with ION Torrent sequencer, 48rxn

G9932C  
HaloPlexHS 1-250kb, ION, 96

HaloPlex Target Enrichment for 1-250kb target region incorporating molecular barcodes and compatible with ION Torrent sequencer, 96rxn

G9932B  
HaloPlexHS 251kb - 2.5Mb, ION, 48

HaloPlex Target Enrichment for 251kb - 2.5Mb target region incorporating molecular barcodes and compatible with ION Torrent sequencer, 48rxn

G9942C  
HaloPlexHS 251kb - 2.5Mb, ION, 96

HaloPlex Target Enrichment for 251kb - 2.5Mb target region incorporating molecular barcodes and compatible with ION Torrent sequencer, 96rxn

G9942B  
HaloPlexHS Prepack Reagents, ILMN, 16

Reagents contained in Box 1 of HaloPlexHS kits for Illumina, sufficient for 16 samples. Probes are excluded.

5190-8629 $1,600.00
HaloPlexHS Prepack Reagents, ILMN, 48

Reagents contained in Box 1 of HaloPlexHS kits for Illumina, sufficient for 48 samples. Probes are excluded.

5190-8630 $4,500.00
HaloPlexHS Prepack Reagents, ILMN, 96

Reagents contained in Box 1 of HaloPlexHS kits for Illumina, sufficient for 96 samples. Probes are excluded.

5190-8631 $7,560.00
HaloPlexHS Prepack Reagents, ION, 16

Reagents contained in Box 1 of HaloPlexHS kits for Ion Torrent, sufficient for 16 samples. Probes are excluded.

5190-8632 $1,600.00
HaloPlexHS Prepack Reagents, ION, 48

Reagents contained in Box 1 of HaloPlexHS kits for Ion Torrent, sufficient for 48 samples. Probes are excluded.

5190-8633 $4,500.00
HaloPlexHS Prepack Reagents, ION, 96

Reagents contained in Box 1 of HaloPlexHS kits for Ion Torrent, sufficient for 96 samples. Probes are excluded.

5190-8634 $7,560.00