SureSelectXT HS Reagent Kits

The SureSelect Target Enrichment System is the most proven target enrichment solution today. This technology enables the capture of genomic targets using long 120 nt RNA baits, which allow for efficient enrichment of regions of interest facilitating confident variant calling.

The SureSelectXT HS Reagent Kit incorporates molecular barcodes to enable more precise variant calling of low-frequency somatic mutations that are often difficult to accurately detect due to tumor heterogeneity. Molecular barcodes enable the detection of variants down to ≤1% variant allele frequency in template DNA molecules by removing false positives and providing error correction for more accurate variant calling. Optimized for FFPE, SureSelectXT HS generates libraries from as little as 10 ng of input from intact or highly fragmented FFPE DNA.

FFPE Optimized

  • Prepare higher complexity libraries from both high- and low- quality DNA
  • Start with as little as 10 ng of DNA input, ideal for limited FFPE specimens

High Sensitivity

  • Eliminate amplification and sequencing artifacts that limit the sensitivity of NGS
  • Leverage molecular barcode for more accurate variant calling through consensus reads
  • Improve sensitivity of low-frequency allele detection, down to 1% or less

Streamlined Workflow

  • Reduce the number of library preparation steps, preventing DNA loss
  • Process samples faster and more efficiently with a 90-minute hybridization and master-mixed reagents
  • Transform samples into sequencing-ready libraries in 8 hours

Reagent kits provide reagents for ligation-based library prep as well as target enrichment including single sample index barcodes and molecular barcodes. 32 sample index barcodes are available in the 16 and 96 rxn kits.

For Research Use Only. Not for use in diagnostic procedures.

Product Catalog Kit Size Quantity Price  
SSel XT HS + 1-499 kb SureSelect XT HS Reagent Kit, index 1-16 + 1-499 kb Target Enrichment Baits, 16 rxn
G9704A  
SSel XT HS 17-32 + 1-499 kb SureSelect XT HS Reagent Kit, index 17-32 + 1-499 kb Target Enrichment Baits, 16 rxn
G9705A  
SSel XT HS 96 + 1-499 kb SureSelect XT HS Reagent Kit, index 1-32 + 1-499 kb Target Enrichment Baits, 96 rxn
G9706A  
SSel XT HS 1-16 + 0.5-2.9 Mb SureSelect XT HS Reagent Kit, index 1-16 + 0.5-2.9 Mb Target Enrichment Baits, 16 rxn
G9704B  
SSel XT HS 17-32 + 0.5-2.9 Mb SureSelect XT HS Reagent Kit, index 17-32 + 0.5-2.9 Mb Target Enrichment Baits, 16 rxn
G9705B  
SSel XT HS 96 + 0.5-2.9 Mb SureSelect XT HS Reagent Kit, index 1-32 + 0.5-2.9 Mb Target Enrichment Baits, 96 rxn
G9706B  
SSel XT HS 1-16 + 3-5.9 Mb SureSelect XT HS Reagent Kit, index 1-16 + 3-5.9 Mb Target Enrichment Baits, 16 rxn
G9704C  
SSel XT HS 17-32 + 3-5.9 Mb, 16 rxn SureSelect XT HS Reagent Kit, index 17-32 + 3-5.9 Mb Target Enrichment Baits, 16 rxn
G9705C  
SSel XT HS 96 + 3-5.9 Mb SureSelect XT HS Reagent Kit, index 1-32 + 3-5.9 Mb Target Enrichment Baits, 96 rxn
G9706C  
SSel XT HS 1-16 + 6-11.9 Mb SureSelect XT HS Reagent Kit, index 1-16 + 6-11.9 Mb Target Enrichment Baits, 16 rxn
G9704D  
SSel XT HS 17-32 + 6-11.9 Mb, 16 rxn SureSelect XT HS Reagent Kit, index 17-32 + 6-11.9 Mb Target Enrichment Baits, 16 rxn
G9705D  
SSel XT HS 96 + 6-11.9 Mb SureSelect XT HS Reagent Kit, index 1-32 + 6-11.9 Mb Target Enrichment Baits, 96 rxn
G9706D  
SSel XT HS 1-16 + 12-24 Mb SureSelect XT HS Reagent Kit, index 1-16 + 12-24 Mb Target Enrichment Baits, 16 rxn
G9704E  
SSel XT HS 17-32 + 12-24 Mb SureSelect XT HS Reagent Kit, index 17-32 + 12-24 Mb Target Enrichment Baits, 16 rxn
G9705E  
SSel XT HS 96 + 12-24 Mb SureSelect XT HS Reagent Kit, index 1-32 + 12-24 Mb Target Enrichment Baits, 96 rxn
G9706E  
SSel XT HS 1-16 + CCP SureSelect XT HS Reagent Kit, index 1-16 + ClearSeq Comprehensive Cancer Target Enrichment Baits, 16 rxn
G9704G  
SSel XT HS 17-32 + CCP SureSelect XT HS Reagent Kit, index 17-32 + ClearSeq Comprehensive Cancer Target Enrichment Baits, 16 rxn
G9705G  
SSel XT HS 96 + CCP SureSelect XT HS Reagent Kit, index 1-32 + ClearSeq Comprehensive Cancer Target Enrichment Baits, 96 rxn
G9706G  
SSel XT HS 1-16 + CREv2 SureSelect XT HS Reagent Kit, index 1-16 + Clinical Research Exome v2 Target Enrichment Baits, 16 rxn
G9704H  
SSel XT HS 17-32 + CREv2 SureSelect XT HS Reagent Kit, index 17-32 + Clinical Research Exome v2 Target Enrichment Baits, 16 rxn
G9705H  
SSel XT HS 96 + CREv2 SureSelect XT HS Reagent Kit, index 1-32 + Clinical Research Exome v2 Target Enrichment Baits, 96 rxn
G9706H  
SSel XT HS 1-16 + CREv2+ SureSelect XT HS Reagent Kit, index 1-16 + Clinical Research Exome v2 Plus Target Enrichment Baits, 16 rxn
G9704J  
SSel XT HS 17-32 + CREv2+ SureSelect XT HS Reagent Kit, index 17-32 + Clinical Research Exome v2 Plus Target Enrichment Baits, 16 rxn
G9705J  
SSel XT HS 96 + CREv2+ SureSelect XT HS Reagent Kit, index 1-32 + Clinical Research Exome v2 Plus Target Enrichment Baits, 96 rxn
G9706J  
SSel XT HS 1-16 + V6 SureSelect XT HS Reagent Kit, index 1-16 + Human All Exon v6 Target Enrichment Baits, 16 rxn
G9704K  
SSel XT HS 17-32 + V6 SureSelect XT HS Reagent Kit, index 17-32 + Human All Exon v6 Target Enrichment Baits, 16 rxn
G9705K  
SSel XT HS 96 + V6 SureSelect XT HS Reagent Kit, index 1-32 + Human All Exon v6 Target Enrichment Baits, 96 rxn
G9706K  
SSel XT HS 1-16 + V6+ SureSelect XT HS Reagent Kit, index 1-16 + Human All Exon v6 Plus Target Enrichment Baits, 16 rxn
G9704L  
SSel XT HS 17-32 + V6+ SureSelect XT HS Reagent Kit, index 17-32 + Human All Exon v6 Plus Target Enrichment Baits, 16 rxn
G9705L  
SSel XT HS 96 + V6+ SureSelect XT HS Reagent Kit, index 1-32 + Human All Exon v6 Plus Target Enrichment Baits, 96 rxn
G9706L